A Cyclin A - Myb-MuvB - Aurora B network regulates the choice between mitotic cycles and polyploid endoreplication cycles.
Michael D. Rotelli, Robert A. Policastro, Anna M. Bolling, Andrew W. Killion, Abraham J. Weinberg, Michael J. Dixon, Gabriel E. Zentner, Claire Walczak, Mary A. Lilly, Brian R. Calvi
The paper identifies a Cyclin A - Myb-MuvB - Aurora B network that regulates the switch from mitotic to endoreplication cycles in Drosophila, showing its role in both developmental and induced endoreplication.
PLoS Genetics · Jul 10, 2019Peer-reviewedDevelopmental Biology