Microbiota during early life windows orchestrates intestinal maturation and barrier formation in the offspring
Cristina Kalbermatter, Sandro Christensen, Irene Keller, Nerea Fernandez Trigo, Joana Carlevaro-Fita, Dorothée L. Berthold, Stephanie C. Talker, Anna S Wenning, Rémy Bruggmann, Uwe Sauer, Mercedes Gomez de Agüero, Andrew James Macpherson, Stephanie Christine Ganal-Vonarburg
This study shows that maternal and postnatal microbiota influence intestinal epithelial maturation and barrier formation through epigenetic and transcriptional mechanisms in offspring.
bioRxiv · Sep 25, 2026 · PreprintMicrobiology