Uwe Sauer

This study shows that spatial prebiotic fermentation in a gut microbiota consortium is driven by metabolic cascades, revealing how spatial gradients influence microbial function and prebiotic efficacy.

The paper develops a minimal marine bacterial community to study crossfeeding interactions and shows how different species exploit metabolic byproducts in a controlled setting.

This study shows that maternal and postnatal microbiota influence intestinal epithelial maturation and barrier formation through epigenetic and transcriptional mechanisms in offspring.

The study examines interactions among marine chitin-degrading bacteria, finding that negative and neutral interactions are common, contrasting with synergistic dynamics observed with other polysaccharides.

This study identifies D-gluconate as a key nutrient source for Salmonella during both acute and chronic infection, supporting its growth in the inflamed gut.

The paper studies bacterial iron acquisition under low carbon conditions and finds that amino acids facilitate iron uptake by E. coli.

The paper examines how resource competition between chitin degraders and GlcNAc exploiters influences community viability and growth dynamics through factors like GlcNAc liberation rates and diffusive loss.

This study shows deep-sea microbes degrade chitin and couple it to extracellular electron transfer using syntrophic interactions in anoxic sediments.

The paper shows that specialized bacteria degrade fucoidans through cooperative interactions, enhancing degradation efficiency by up to 97.1%.

The paper shows that EPS from chitin degradation influences microbial community diversity by supporting different consumer types through sequential breakdown.

This study investigates how AI-2 signaling and chemotaxis in E. coli influence its competitive interaction with Salmonella Typhimurium in the gut, affecting colonization resistance and metabolism.

The paper identifies input signals for 41 Escherichia coli transcription factors by correlating metabolomics and transcriptomics data, validating predictions through in vitro assays.

This study identifies context-dependent and -independent carbohydrates used by Salmonella Typhimurium for gut colonization in mice, highlighting D-glucose, D-fructose, and D-galactose as key substrates.

This study introduces a method using microbial enzyme cocktails to quantify polysaccharides, demonstrating effectiveness for chitin and laminarin with low detection limits.

The paper identifies fucose-rich oligosaccharides in deep ocean seawater, showing their selective preservation compared to surface ocean samples.

The paper uses dynamic metabolomics to identify potential TOR signaling genes in yeast by analyzing metabolite responses to rapamycin treatment.

The paper investigates trade-offs in microbial central carbon metabolism, showing that glycolytic and gluconeogenic pathways cannot be optimized simultaneously due to regulatory limitations.

The paper identifies bulk autophagy and β-oxidation as critical energy providers during acute glucose starvation in yeast.

The paper integrates metabolomics and genomics data to identify functional SNPs in Mycobacterium tuberculosis strains, revealing genetic basis for antibiotic sensitivity.

The paper characterizes two propionate catabolism pathways in mycobacteria, showing the methylcitrate pathway's high capacity and the methylmalonyl pathway's detoxification role.

This study integrates metabolomics, phosphoproteomics, and transcriptomics data in yeast to identify regulatory mechanisms linking signaling kinases to metabolic changes.