Galectin-1 induces macrophage immunometabolic reprogramming, modulates T cell immunity and attenuates atherosclerotic plaque formation
Ya Li, Julian Leberzammer, Xavier Blanchet, Rundan Duan, Michael Lacy, Vasiliki Triantafyllidou, Veit Eckardt, Eva Briem, Anna Simone Jung, Rui Jun Su, Joel Guerra, Yvonne J. F. M. Jansen, Michael Hristov, Wolfgang Enard, Jürgen Bernhagen, , Philipp von Hundelshausen
This study shows that Galectin-1 reduces atherosclerotic plaque formation by reprogramming macrophages and modulating T cell immunity through both glycan-dependent and -independent mechanisms.
Atherosclerosis · Dec 4, 2025Peer-reviewedImmunology