Christian Weber

The paper identifies miR-210-5p as a nuclear hypoxamiR that directly binds HIF-1 and enhances HIF-dependent transcription, revealing a new RNA-mediated regulatory mechanism.

This paper shows that blocking endothelial CB1 receptors reduces arterial inflammation and lipid uptake under atheroprone shear stress, suggesting potential therapeutic benefits for atherosclerosis.

This study compares two myocardial infarction models, showing the intact-chest model better reflects human immune responses and identifies immature neutrophils as contributors to cardiac dysfunction.

The paper identifies MIF-2-CCL20 complex formation in liver fibrosis through biochemical and computational methods, showing its role in modulating immune and stromal responses.

This study shows that neural CXCR4 reduces atherosclerotic plaque formation in mice without affecting metabolism or immune cells, and identifies MIF-CXCR4 signaling in the PVN as a potential neuroimmune pathway in atherosclerosis.

This study shows that Galectin-1 reduces atherosclerotic plaque formation by reprogramming macrophages and modulating T cell immunity through both glycan-dependent and -independent mechanisms.

The paper identifies self-reactive B cells in atherosclerosis-associated tertiary lymphoid organs that produce high-affinity autoantibodies contributing to disease progression.

This study shows that gut microbial metabolite imidazole propionate impairs endothelial function and promotes atherosclerosis in both human and animal models.

This study shows that Olfr2 promotes abdominal aortic aneurysm by enhancing CX3CR1-mediated monocyte recruitment through inflammatory pathways.

This study identifies the Nfe2l1-Atf3 pathway as a regulator of cholesterol-induced adipocyte inflammation and insulin resistance in both human and mouse models.

This paper introduces a shortwave infrared Raman imaging technique that enables label-free, high-contrast visualization of tissue composition and pathology without contrast agents.

This paper shows that miR-26b deficiency worsens MASH in mice, and that miR-26b mimic-loaded LNPs can reverse these effects.