Rui Jun Su

This study shows fumarate impairs ATR-CHK1 signaling by succinating RPA1, leading to defective DNA repair and cell cycle control in FH-dRCC.

This study shows that Galectin-1 reduces atherosclerotic plaque formation by reprogramming macrophages and modulating T cell immunity through both glycan-dependent and -independent mechanisms.

This study identifies two critical m6A-regulated developmental windows in human erythropoiesis, showing m6A-MTase activity is essential for proliferation and differentiation in BFU-E and CFU-E.

This study identifies PTPN1 and PTPN2 as cooperative regulators of cancer immune evasion, showing their inhibition enhances immune response and synergizes with anti-PD1 therapy.