Machine Learning Uncovers the Transcriptional Regulatory Network for the Production Host Streptomyces albidoflavus
Mathias Jönsson, Renata Sigrist, Tetiana Gren, Mykhaylo Semenov Petrov, Nils Emil Junge Marcussen, Anna Svetlova, Pep Charusanti, Peter Gockel, Bernhard Ørn Palsson, Lei Yang, Emre Özdemir
The paper uses independent component analysis to characterize the transcriptional regulatory network of Streptomyces albidoflavus and identifies iModulons that describe its activity across growth conditions.
bioRxiv · Jan 9, 2024 · PreprintGenomics