Author

Anna Tangiyan

Children's Hospital of Philadelphia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Bioinformatics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

AbdulKareem A. AlShaheeb· 1 shared Adebola A. Owolabi· 1 shared Alberto BosqueiD· 1 shared Anupama JhaiD· 1 shared Benjamin D Wales-McGrathiD· 1 shared Deanna C. Clemmer· 1 shared Di WuiD· 1 shared Elyse K. McMahoniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

AbdulKareem A. AlShaheeb

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2 papers

Recent·Most cited

Generative modeling for RNA splicing predictions and design

Di Wu, Natalie Maus, Anupama Jha, Kevin Yang, Benjamin D Wales-McGrath, San Jewell, Anna Tangiyan, Peter S. Choi, Jacob R. Gardner, Yoseph Barash

This paper introduces TrASPr+BOS, a generative AI model for predicting and designing RNA to achieve tissue-specific splicing outcomes, showing improved performance over existing methods.

eLife · May 29, 2026Peer-reviewedBioinformatics

Glucose-Fueled Histone Modifications Drive HIV-1 Latency Reversal at Hypoxia

Yetunde I. Kayode, Deanna C. Clemmer, Adebola A. Owolabi, AbdulKareem A. AlShaheeb, Elyse K. McMahon, Anna Tangiyan, Lauren Clark, Glenn E. Simmons, Alberto Bosque, Melanie R. McReynolds, Harry E. Taylor

This study identifies glucose and oxygen as critical metabolic factors influencing HIV-1 latency reversal, showing that glucose fuels histone lactylation and chromatin accessibility at the HIV promoter.

bioRxiv · Sep 14, 2025 · PreprintImmunology