Secreted exosomes induce filopodia formation
Caitlin McAtee, Mikin M. Patel, Daisuke Hoshino, Bong Hwan Sung, Ariana K. von Lersner, Mingjian Shi, Nan Hyung Hong, Anna Young, Evan Krystofiak, Andries Zijlstra, Alissa M. Weaver
This study identifies exosomes carrying THSD7A as regulators of filopodia formation in both cancer cells and neurons, mediated through Cdc42 activation.
eLife · Dec 5, 2025Peer-reviewedCell Biology