Bong Hwan Sung

Fluid shear stress modulates endocytic pathways and junctional targeting of tumor-derived extracellular vesicles in endothelial cells

This study investigates how fluid shear stress affects the uptake and junctional targeting of tumor-derived extracellular vesicles by endothelial cells, identifying clathrin- and caveolin-mediated endocytosis as key pathways.

Secreted exosomes induce filopodia formation

This study identifies exosomes carrying THSD7A as regulators of filopodia formation in both cancer cells and neurons, mediated through Cdc42 activation.

Exosomes are specialized vehicles to induce fibronectin assembly

This study shows that exosomes initiate fibronectin assembly in vitro and in vivo, reducing tumor growth and fibrosis.