Characterisation of distinct senescent-like T cell populations during healthy and unhealthy ageing
Conor Garrod-Ketchely, Lauren A. Callender, Johannes Schroth, Katie Littlewood, Elizabeth C. Carroll, Dina Tamsan, Victoria Tsang, Isabell Nessel, Natalie E. Riddell, Benny Chain, Dunja Aksentijević, Daniel Harding, Federica M. Marelli‐Berg, Jonas Byström, Melissa Pereira Da Costa, , Siân M. Henson
This study identifies a distinct senescent-like CD8 TEMRA cell population in older individuals with type 2 diabetes, linked to metabolic inflammation and impaired immune function.
bioRxiv · Jun 16, 2025 · PreprintImmunology