Annekatrin König

This study shows that glycation of alpha-synuclein increases its aggregation and neuroinflammatory responses, linking type 2 diabetes and Parkinson's disease.

The paper shows that alpha-synuclein oligomers activate NFAT, leading to neuronal toxicity and synaptic loss, which can be reversed by NFAT inhibitors.

This study shows doxycycline reduces α-synuclein aggregation and oxidative stress in vitro and in vivo, suggesting it could treat synucleinopathies like Parkinson's disease.

The paper evaluates pharmacological modulators of α-synuclein and tau aggregation and internalization, identifying compounds that reduce their aggregation and spread.