The yeast core spliceosome maintains genome integrity through R-loop prevention and alpha-tubulin expression
Annie S. Tam, Veena Mathew, Tianna S. Sihota, Anni Zhang, Peter C. Stirling
This study shows that yeast splicing defects cause genome instability through gene expression changes and R-loop accumulation, which is worsened by loss of Mad1.
bioRxiv · Feb 28, 2018 · PreprintCell Biology