Author

Tianna S. Sihota

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Cell Biology· 1

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Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:yeast· 1

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Anni Zhang· 1 shared Annie S. Tam· 1 shared Peter C. StirlingiD· 1 shared Veena MathewiD· 1 shared

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Anni Zhang

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1 paper

Recent·Most cited

Cell BiologybioRxivPreprintFeb 28, 2018

The yeast core spliceosome maintains genome integrity through R-loop prevention and alpha-tubulin expression

Annie S. Tam, Veena Mathew, Tianna S. Sihota…·Peter C. Stirling

This study shows that yeast splicing defects cause genome instability through gene expression changes and R-loop accumulation, which is worsened by loss of Mad1.

DOI 10.1101/272807

yeastgenetic perturbation / CRISPR

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