Author

Annie J. Zalon

University of Michigan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Danielle M. DiFrancoiD· 2 shared Hayley S. McLoughliniD· 2 shared Kristen H. SchusteriD· 2 shared Nicholas R. Stec· 2 shared Yuanfang GuaniD· 2 shared Zaid Haque· 2 shared Alexandra F. PutkaiD· 1 shared Amanda M. Pierce· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersNeuroscience

Danielle M. DiFrancoORCID

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2 papers

Recent·Most cited

NeuroscienceMolecular TherapyPeer-reviewedFeb 29, 2024

ASOs are an effective treatment for disease-associated oligodendrocyte signatures in premanifest and symptomatic SCA3 mice

Kristen H. Schuster, Annie J. Zalon, Danielle M. DiFranco…·Hayley S. McLoughlin

This study shows that ASO treatment rescues oligodendrocyte dysfunction in SCA3 mice by targeting mutant ATXN3, suggesting potential for glial-targeted therapies in neurodegenerative diseases.

24 citations

mouseexperimental assay

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NeuroscienceJournal of NeurosciencePeer-reviewedJan 18, 2022

Impaired oligodendrocyte maturation is an early feature in SCA3 disease pathogenesis

Kristen H. Schuster, Annie J. Zalon, Hongjiu Zhang…·Hayley S. McLoughlin

This study identifies impaired oligodendrocyte maturation as an early feature in SCA3 disease pathogenesis through longitudinal transcriptomic analysis and functional validation in mice.

55 citationstop 3%

mousebulk RNA-seq

𝕏 PostBluesky