BiochemistrybioRxivPreprint
MASH-in-a-dish reveals fatty acid-driven itaconate crosstalk between Kupffer cells and hepatocytes
Jung-Chin Chang, Annika Sullock Enzlin, Maya W. Haaker…·Celia R. Berkers
The paper develops an in vitro MASH model to study metabolite crosstalk between Kupffer cells and hepatocytes, identifying itaconate as a key mediator of liver disease progression.
DOI 10.64898/2026.10.31.763289