Author

Anthony Bosco

Primary ORCID profile (0000-0002-4335-615X · 4 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Anthony BoscoiD4 papers · University of Arizona

Biology Disciplines

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Immunology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Niamh Troy· 2 shared Alexander M. Gout· 1 shared Anthony Kicic· 1 shared Anya C. Jones· 1 shared Anya Jones· 1 shared Christian Pasquali· 1 shared Christopher McCrae· 1 shared Deborah Strickland· 1 shared

Activity by Year

2016-2017 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCell Biology

Niamh Troy

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Airway IRF7hi versus IRF7lo molecular response patterns determine clinical phenotypes in children with acute wheezing

Siew-Kim Khoo, James Read, Kimberley Franks, Guicheng Zhang, Joelene Bizzintino, Laura Coleman, Christopher McCrae, Lisa Öberg, Niamh Troy, Franciska Prastanti, Janet Everard, Stephen Oo, Meredith L Borland, Rose A Maciewicz, Peter N Le Souëf, , Anthony Bosco

The paper identifies IRF7hi and IRF7lo molecular phenotypes in children with acute wheezing, showing distinct clinical outcomes related to symptom duration and hospital admission.

bioRxiv · Nov 21, 2017 · PreprintCell Biology

Protection against maternal infection-associated fetal growth restriction - proof-of-concept with a microbial-derived immunomodulator OM85: safety and efficacy data

Naomi Scott, Jeff Lauzon-Joset, Anya Jones, Kyle Mincham, Niamh Troy, Jonatan Leffler, Michael Serralha, Susan Prescott, Sarah Robertson, Christian Pasquali, Anthony Bosco, Patrick Holt, Deborah Strickland

This study shows that OM85, an immunomodulator, reduces fetal loss and growth restriction in pregnant mice exposed to bacterial LPS or influenza, by modulating maternal inflammatory responses without impairing anti-microbial defenses.

Mucosal Immunology · May 1, 2017Peer-reviewedImmunology

Persistent activation of interlinked Th2-airway epithelial gene networks in sputum-derived cells from aeroallergen-sensitized symptomatic atopic asthmatics

Anya C. Jones, Niamh M. Troy, Elisha White, Elysia M. Hollams, Alexander M. Gout, Kak-Ming Ling, Anthony Kicic, Peter D Sly, Patrick G Holt, Graham L Hall, Anthony Bosco

The paper identifies distinct gene networks in sputum-derived cells from atopic asthmatics with and without wheezing, highlighting Th2 and epithelial gene interactions in asthmatics.

bioRxiv · Jul 13, 2016 · PreprintImmunology