Michael Serralha

The paper tracks the upper airway microbiome changes in preschool children and links them to asthma-associated persistent wheeze, showing that bacterial shifts precede viral infections and symptoms in sensitized children.

This study shows that OM85, an immunomodulator, reduces fetal loss and growth restriction in pregnant mice exposed to bacterial LPS or influenza, by modulating maternal inflammatory responses without impairing anti-microbial defenses.

The paper examines the infant airway microbiome's role in asthma development by analyzing viral and bacterial communities in nasopharyngeal samples from a birth cohort.