Demonstration and structural basis of a therapeutic DNA aptamer for SARS-CoV-2 spike protein detection
Yujun Liu, Kaidong Wang, Weiguang Wang, Saarang Kashyap, Jonathan Jih, Anthony Imani, Tzung K. Hsiai, Z. Hong Zhou
This paper develops a rapid, specific, and reusable DNA aptamer-based biosensor for detecting SARS-CoV-2 spike protein, demonstrating high sensitivity and structural insights through cryo-EM.
bioRxiv · Mar 14, 2025Bioengineering