Author

Jonathan Jih

California NanoSystems InstituteORCID 0000-0001-5169-0919Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2 Bioengineering· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Assay:cryo-EM· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:deep learning· 1 Assay:electronic health records· 1 Research Focus:host-pathogen & immune response· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Z. Hong ZhouiD· 4 shared Saarang KashyapiD· 2 shared Yun-Tao LiuiD· 2 shared Alexander StevensiD· 1 shared Ana L. Alvarez-CabreraiD· 1 shared Anthony Imani· 1 shared Ethan H. CrofutiD· 1 shared Fenyong Liu· 1 shared

Activity by Year

2018-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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4 shared papersMicrobiology

Z. Hong ZhouORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Cell BiologyMicroscopy and MicroanalysisPeer-reviewedJul 1, 2026

IsoNet2 determines cellular structures at submolecular resolution without averaging

Yun-Tao Liu, Hongcheng Fan, Jonathan Jih…·Z. Hong Zhou

IsoNet2 reconstructs high-resolution 3D cellular structures from cryogenic electron tomography without averaging.

20 citationstop 1%

electronic health recordsdeep learning

𝕏 PostBluesky

BioengineeringBiosensors and BioelectronicsPeer-reviewedNov 1, 2025

Demonstration and structural basis of a therapeutic DNA aptamer for SARS-CoV-2 spike protein detection

Yujun Liu, Kaidong Wang, Weiguang Wang…·Z. Hong Zhou

This paper develops a rapid, specific, and reusable DNA aptamer-based biosensor for detecting SARS-CoV-2 spike protein, demonstrating high sensitivity and structural insights through cryo-EM.

2 citations

proteomicsexperimental assay

𝕏 PostBluesky

MicrobiologyJournal of VirologyPeer-reviewedJul 3, 2025

Structure of a new capsid form and comparison with A-, B- and C-capsids clarify herpesvirus assembly and DNA translocation

Alexander Stevens, Saarang Kashyap, Ethan H. Crofut…·Z. Hong Zhou

This study identifies a new D-capsid type in herpesvirus assembly, revealing structural dynamics of DNA translocation and clarifying the origins of empty and DNA-filled capsids.

5 citations

𝕏 PostBluesky

MicrobiologybioRxivPreprintSep 18, 2018

Different capsid-binding patterns of the β-herpesvirus-specific tegument protein pp150 (pM32/pUL32) in murine and human cytomegaloviruses

Wei Liu, Xinghong Dai, Jonathan Jih…·Z. Hong Zhou

This study compares the capsid-binding patterns of pp150 in human and murine cytomegaloviruses using cryoEM, revealing structural differences and functional implications for using MCMV as a model for HCMV.

DOI 10.1101/420604

𝕏 PostBluesky