A robust platform for recombinant production of animal venom toxin modulators of ion channels
Jose Enrique Gonzalez-Prada, Alexander S. Haworth, Jacob I Browne, Samantha C. Salvage, Nicola Secomandi, Anthony M. Rush, Anne Ritoux, Maya Dannawi, Leonard Lee, Vasiliki Mavridou, Yin Yao Dong, Ewan St. John Smith, Antony Philip Jackson, Edward B. Stevens, Paul S. Miller
This paper develops a method to produce animal venom toxins using recombinant Fc-fusion proteins, achieving high yields and functionality for various toxin types.
bioRxiv · Jun 11, 2025 · PreprintPharmacology & Toxicology