Antony Philip Jackson

Structural implications of glycosylation on the voltage-gated sodium channel β3-subunit

This paper investigates the structural impact of glycosylation on the β3-subunit of voltage-gated sodium channels using glycan profiling and molecular dynamics simulations.

A robust platform for recombinant production of animal venom toxin modulators of ion channels

This paper develops a method to produce animal venom toxins using recombinant Fc-fusion proteins, achieving high yields and functionality for various toxin types.

Isoform-specific N-linked glycosylation of voltage-gated sodium channel alpha-subunits alters beta-subunit binding sites

This study uses molecular modeling and simulations to show that N-linked glycans on Nav channel alpha-subunits may block beta-subunit Ig-domain binding and influence channel clustering.