Cell BiologyMolecular CellPeer-reviewed
The antibacterial factor APOL3 couples lysosomal damage to mitochondrial DNA efflux and type I IFN induction
Dominic A. Ritacco, Hamna Shahnawaz, Antonia Oduguwa…·Ryan G. Gaudet
This study shows APOL3 links lysosomal damage to mitochondrial DNA release and type I IFN production via BAK/BAX pores and cGAS/STING signaling.
7 citationstop 1%