Author

Jacob Hawk

Columbia University Irving Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:ATAC-seq· 1 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Abbas NaziriD· 1 shared Antonia Oduguwa· 1 shared Brianna Vizcaino· 1 shared Charles L. SawyersiD· 1 shared Christina S. LeslieiD· 1 shared Dominic A. Ritacco· 1 shared Donna L. FärberiD· 1 shared Erik LadewigiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperGenomics

Abbas NazirORCID

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Author profile →

2 papers

Recent·Most cited

The antibacterial factor APOL3 couples lysosomal damage to mitochondrial DNA efflux and type I IFN induction

Dominic A. Ritacco, Hamna Shahnawaz, Antonia Oduguwa, Jacob Hawk, Brianna Vizcaino, Donna L. Färber, Ryan G. Gaudet

This study shows APOL3 links lysosomal damage to mitochondrial DNA release and type I IFN production via BAK/BAX pores and cGAS/STING signaling.

Molecular Cell · Feb 24, 2026Peer-reviewedCell Biology

FOXA1 mutations co-opt nascent transcription factor networks in partnership with androgen receptor to enhance prostate tumorigenicity

Erik Ladewig, Abbas Nazir, Tyler Park, Vinson B. Fan, Zhendong Cao, Jacob Hawk, Lauren Kelly, Robert Tjian, Christina S. Leslie, Charles L. Sawyers

This study identifies FOXA1 mutations in prostate cancer, showing they alter chromatin accessibility and promote tumorigenicity by reprogramming cell fate through interactions with androgen receptor and POU2F1.

Cell Reports · Jan 31, 2026Peer-reviewedGenomics