Author

Antonis A. Karamalegos

University of Kent

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2

Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:metagenomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Laura May Freeman· 2 shared Marina EzcurraiD· 2 shared Mireya Vazquez-PradaiD· 2 shared Nathan DennisiD· 2 shared Brigita Kudzminkaite· 1 shared Feng Xue· 1 shared Ian R. BrowniD· 1 shared Imogen Langley· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersPhysiology

Laura May Freeman

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2 papers

Recent·Most cited

A defined microbial community remodels host metabolism and pathogen resistance in Caenorhabditis elegans

Nathan Dennis, Laura May Freeman, Mireya Vazquez-Prada, Imogen Langley, Madison S. Mortensen, Antonis A. Karamalegos, Jennifer Watts, Marina Ezcurra

This study shows that a defined microbial community remodels host metabolism and pathogen resistance in C. elegans by altering transcriptional pathways and physiological traits.

bioRxiv · Sep 10, 2026 · PreprintPhysiology

A gut-microbiota-muscle axis that protects against age-related motor decline by regulating mitochondrial fission in C. elegans

Nathan Dennis, Mireya Vazquez-Prada, Laura May Freeman, Feng Xue, Lisa-Jane White, Antonis A. Karamalegos, William G. Sullivan, Brigita Kudzminkaite, Ian R. Brown, Jennifer R. Hiscock, Marina Ezcurra

This study identifies a gut microbiota-muscle axis in C. elegans that protects against age-related motor decline by regulating mitochondrial fission through DRP-1.

iScience · Nov 20, 2025Peer-reviewedPhysiology