Ian R. Brown

From Magnetosomes to Vesicles: LemA Proteins as Drivers of Bacterial Membrane Reorganization

This paper identifies LemA proteins as conserved drivers of bacterial membrane reorganization, involved in organelle and vesicle formation through interactions with divisome components and other membrane remodeling factors.

Three-dimensional single-particle reconstruction by atomic force microscopy allows rapid structural-based validation of recombinant SARS-CoV-2 Spike protein from a single topology image

This paper develops a method to perform three-dimensional single-particle reconstruction using AFM for rapid structural validation of proteins, demonstrated on SARS-CoV-2 Spike protein.

A gut-microbiota-muscle axis that protects against age-related motor decline by regulating mitochondrial fission in C. elegans

This study identifies a gut microbiota-muscle axis in C. elegans that protects against age-related motor decline by regulating mitochondrial fission through DRP-1.

Next generation protein-based materials capture and preserve projectiles from supersonic impacts

This paper develops a protein-based material that absorbs supersonic impacts and preserves projectiles, demonstrating its effectiveness in capturing and preserving hypervelocity projectiles.

Exceptional yield vesicle packaged recombinant protein production from E. coli.

This paper describes a system for producing functional recombinant proteins in extracellular vesicles from E. coli, achieving high yields and enabling continuous isolation.

Neuronal SKN-1B Modulates Nutritional Signalling Pathways and Mitochondrial Networks to Control Satiety

This study identifies SKN-1B in C. elegans as a central food-responsive node that controls satiety and metabolic homeostasis by modulating endocrine pathways and mitochondrial networks.