Genotype-free individual genome reconstruction of Multiparental Population Models by RNA sequencing data
Kwangbom Choi, Michael W. Lloyd, Hao He, Daniel M. Gatti, Vivek M. Philip, Narayanan Raghupathy, Mathew Vincent, Sai Lek, Isabela Gerdes Gyuricza, Steven C. Munger, Alan D. Attie, Mark Keller, Elissa J. Chesler, Karl W. Broman, Anuj Srivastava, Gary A. Churchill
The paper introduces GBRS, a method to reconstruct diploid genomes and quantify gene expression in multi-parent populations using RNA-Seq data without requiring genotype information.
bioRxiv · Oct 11, 2020 · PreprintBioinformatics