Author

Alan D. Attie

University of Wisconsin–Madison

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Genetics· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Organism:mouse· 3 Approach:statistical model· 3 Research Focus:differential expression· 1 Research Focus:fine-mapping· 1 Research Focus:gene regulatory network inference· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Mark P. KelleriD· 2 shared Aimee Teo Broman· 1 shared Angie T. Oler· 1 shared Anuj Srivastava· 1 shared Bailey A. KnopfiD· 1 shared Brian S. YandelliD· 1 shared Bruno Hagenbuch· 1 shared Cara L. GreeniD· 1 shared

Activity by Year

2015-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersPhysiology

Mark P. KellerORCID

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Author profile →

3 papers

Recent·Most cited

Lifelong restriction of dietary valine has sex-specific benefits for health and lifespan in mice

Mariah F. Calubag, Ismail Ademi, Cara L. Green, Dulmalika N. H. Manchanayake, Hashan S. M. Jayarathne, Ryan N. Marshall, Sandra M. Le, Penelope Lialios, Lucia E. Breuer, Shoshana Yakar, Reji Babygirija, Michelle M. Sonsalla, Isaac Grunow, Chung-Yang Yeh, Yang Liu, , Dudley W. Lamming

This study shows that lifelong dietary valine restriction improves healthspan and extends lifespan in male mice but not females, with distinct molecular effects in different tissues.

Nature Aging · Jul 24, 2026Peer-reviewedPhysiology

Genotype-free individual genome reconstruction of Multiparental Population Models by RNA sequencing data

Kwangbom Choi, Michael W. Lloyd, Hao He, Daniel M. Gatti, Vivek M. Philip, Narayanan Raghupathy, Mathew Vincent, Sai Lek, Isabela Gerdes Gyuricza, Steven C. Munger, Alan D. Attie, Mark Keller, Elissa J. Chesler, Karl W. Broman, Anuj Srivastava, Gary A. Churchill

The paper introduces GBRS, a method to reconstruct diploid genomes and quantify gene expression in multi-parent populations using RNA-Seq data without requiring genotype information.

bioRxiv · Oct 11, 2020 · PreprintBioinformatics

Identification of Slco1a6 as a candidate gene that broadly affects gene expression in mouse pancreatic islets

Jianan Tian, Mark P. Keller, Angie T. Oler, Mary E. Rabaglia, Kathryn L. Schueler, Donald S. Stapleton, Aimee Teo Broman, Wen Zhao, Christina Kendziorski, Brian S. Yandell, Bruno Hagenbuch, Karl W Broman, Alan D. Attie

The paper identifies Slco1a6 as a gene affecting gene expression in mouse pancreatic islets through eQTL analysis and functional studies.

bioRxiv · Aug 28, 2015Genetics