Isabela Gerdes Gyuricza

The paper analyzes the spread of Plasmodium falciparum with hrp2/3 deletions in Peru, finding that demographic changes from malaria control and potential selection pressures drove their fixation.

The paper identifies a composite transcriptome signature with high distal heritability that explains 30% of metabolic trait variation across species.

The paper models metabolic disease susceptibility and resilience in genetically diverse mice by analyzing diet-induced metabolic responses across three strains.

The paper identifies three genetic loci influencing mitochondrial proteins and heart hypertrophy in mice using proteomics and association mapping.

QTLViewer provides an interactive webtool for QTL mapping and exploration in CC and DO mouse populations, enhancing accessibility to genetic analysis resources.

The paper identifies genetic drivers of protein phosphorylation using multi-omics data from mouse tissues, revealing novel interactions and targets of PDK1 in obesity and diabetes.

The paper analyzes transcriptome and proteome data from aged mouse hearts to identify molecular changes associated with aging, revealing distinct biological processes and genetic loci influencing age-related changes.

This study profiles mRNA and protein levels in aging kidneys, finding that protein changes reveal more extensive and functionally significant aging-related alterations than mRNA.

The paper introduces GBRS, a method to reconstruct diploid genomes and quantify gene expression in multi-parent populations using RNA-Seq data without requiring genotype information.

The paper investigates HSPG2 as a modifier gene for Marfan syndrome, finding lower HSPG2 expression in mice with severe phenotypes.