Revealing and evaluation of antivirals targeting multiple druggable sites of RdRp complex in SARS-CoV-2
Ruchi Rani, Sanketkumar Nehul, Shweta Choudhary, Anushka Upadhyay, Gaurav Kumar Sharma, Pravindra Kumar, Shailly Tomar
This study identifies antivirals targeting multiple sites of SARS-CoV-2 RdRp complex through in-silico screening, SPR validation, and cell-based assays, showing potent antiviral effects.
bioRxiv · Jul 24, 2023 · PreprintMolecular Biology