Cancer BiologybioRxivPreprint
Chronic Antigen Stimulation in Solid Tumors Induces T Cell Exhaustion and Limits Efficacy of T Cell Bispecific Therapies
Idil Hutter-Karakoc, Eleni Maria Varypataki, Aparna Neelakandhan…·Maria Amann
This study shows that chronic antigen exposure leads to T cell exhaustion, reducing the effectiveness of T cell bispecific therapies in solid tumors.
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