Author

Marine Richard

F. Hoffmann-La Roche AGORCID 0000-0002-6752-0129Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Ahmet VaroliD· 1 shared Aparna Neelakandhan· 1 shared Christian KleiniD· 1 shared Christian MünziD· 1 shared Dario Venetz· 1 shared Eleni Maria Varypataki· 1 shared Idil Hutter-KarakociD· 1 shared Maria AmanniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Ahmet VarolORCID

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1 paper

Recent·Most cited

Chronic Antigen Stimulation in Solid Tumors Induces T Cell Exhaustion and Limits Efficacy of T Cell Bispecific Therapies

Idil Hutter-Karakoc, Eleni Maria Varypataki, Aparna Neelakandhan, Simone Lang, Vesna Kramar, Ahmet Varol, Sasha Simons, Marine Richard, Mudita Pincha, Dario Venetz, Nicole Joller, Christian Münz, Pablo Umaña, Christian Klein, Maria Amann

This study shows that chronic antigen exposure leads to T cell exhaustion, reducing the effectiveness of T cell bispecific therapies in solid tumors.

bioRxiv · Jan 29, 2025 · PreprintCancer Biology