Author

April Lu

University of California, Davis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

Alam X León Cardona· 1 shared Andrew J. FisheriD· 1 shared Carlos H. Trasviña‐ArenasiD· 1 shared Melody MalekiD· 1 shared Mohammad H. HashemianiD· 1 shared Sheila S. DavidiD· 1 shared Tian XiaiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Alam X León Cardona

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1 paper

Recent·Most cited

Structural Connectivity Between the Zinc Linchpin Motif, the cluster, and the active site orchestrates DNA repair in MUTYH

Mohammad H. Hashemian, Melody Malek, Tian Xia, April Lu, Alam X León Cardona, Andrew J. Fisher, Carlos H. Trasviña‐Arenas, Sheila S. David

This study presents MUTYH crystal structures showing how the Zn linchpin and Fe-S cluster interact to facilitate DNA repair, revealing how mutations disrupt this process.

bioRxiv · May 30, 2026 · PreprintBiochemistry