Author

Tian Xia

University of California, DavisORCID 0000-0003-0123-1305Unclaimed ORCID profile · follow to get notified of new preprints

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Tian Xia14 papers · Huazhong University of Science and Technology

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

Alam X León Cardona· 1 shared Andrew J. FisheriD· 1 shared April Lu· 1 shared Carlos H. Trasviña‐ArenasiD· 1 shared Melody MalekiD· 1 shared Mohammad H. HashemianiD· 1 shared Sheila S. DavidiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Alam X León Cardona

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintMay 30, 2026

Structural Connectivity Between the Zinc Linchpin Motif, the cluster, and the active site orchestrates DNA repair in MUTYH

Mohammad H. Hashemian, Melody Malek, Tian Xia…·Sheila S. David

This study presents MUTYH crystal structures showing how the Zn linchpin and Fe-S cluster interact to facilitate DNA repair, revealing how mutations disrupt this process.

DOI 10.64898/2026.05.27.728240

humanstructural biology

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