Kinetics of local C3 production orchestrates neutrophil recruitment in lung injury
Rafael Aponte Alburquerque, Josué Isaí Portillo Hernández, Aasritha Nallapu, Marick Starick, Jungheun Hyun, John Michael Sanchez, Neelou S. Etesami, Sandip K. Mukherjee, Ayşe Naz Ozantürk, Jose Vazquez, Allison Chang, Ashley Zheng, Lorena Garnica, Alberto E. Lopez, Andrew E. Gelman, , Hrishikesh S. Kulkarni
This study shows lung-derived C3 initiates neutrophil recruitment in pneumonia before systemic C3, highlighting local complement's role in mucosal immunity.
Mucosal Immunology · Oct 1, 2026Peer-reviewedImmunology