Aasritha Nallapu

This study shows lung-derived C3 initiates neutrophil recruitment in pneumonia before systemic C3, highlighting local complement's role in mucosal immunity.

This study shows that C3 modulates trained immunity in alveolar macrophages via C3aR signaling, enhancing glycolytic activity and cytokine output.

This study shows that locally produced complement factor B in the gut reduces colitis, highlighting its role in mucosal immunity.