Ashwini R. Shende

Gene circuit-driven amplified selection enables evolution of fast-growing Escherichia coli

This paper shows that a synthetic gene circuit can break a growth rate plateau in E. coli by selectively suppressing slow-growing cells, leading to faster growth.

Engineering microbial consortia for distributed signal processing

This paper introduces a method using microbial consortia and computational models to decode complex signals and predict input concentrations from microbial community responses.

A foundation model for microbial growth dynamics

This paper develops a foundation model for microbial growth dynamics using self-supervised learning on diverse datasets, enabling accurate reconstruction and prediction of growth patterns and antibiotic responses.