Epithelial zonation along the mouse and human small intestine defines five discrete metabolic domains
Rachel K. Zwick, Petr Kašpárek, Brisa Palikuqi, Sara Viragova, Laura Weichselbaum, Christopher S. McGinnis, Kara L. McKinley, Asoka Rathnayake, Dedeepya Vaka, Vinh Q Nguyen, Coralie Trentesaux, Efren A. Reyes, Alexander R. Gupta, Zev J. Gartner, Richard M. Locksley, , Ophir D. Klein
The paper identifies five discrete metabolic domains in the mouse and human small intestine using transcriptional signatures and machine learning, showing how diet influences domain properties.
Nature Cell Biology · Feb 1, 2024Peer-reviewedGenomics