Author

Astrid van Rens

Radboud University Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1

Frequent Co-Authors

Dirk J. LefeberiD· 2 shared Anna M. de KortiD· 1 shared Anthony H.V. SchapiraiD· 1 shared Catharina J.M. KlijniD· 1 shared Deepak Ailani· 1 shared Floris H.B.M. SchreuderiD· 1 shared H. Bea KuiperijiD· 1 shared Hai Hoang Bui· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersNeuroscience

Dirk J. LefeberORCID

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2 papers

Recent·Most cited

Translational validation of shotgun proteomics findings in cerebrospinal fluid of sporadic cerebral amyloid angiopathy patients

Marc Vervuurt, Anna M. de Kort, Iris Kersten, Astrid van Rens, Catharina J.M. Klijn, Floris H.B.M. Schreuder, Dirk J. Lefeber, H. Bea Kuiperij, Marcel M. Verbeek

The paper validates potential biomarkers for sporadic cerebral amyloid angiopathy in human CSF, finding no significant differences in CTSB and CTSS levels but a decrease in HEXA activity.

bioRxiv · Jan 15, 2024 · PreprintNeuroscience

Unexpected opposing biological effect of genetic risk factors for Parkinson disease

Marcus Keatinge, Matthew E. Gegg, Lisa Watson, Heather Mortiboys, Nan Li, Mark Dunning, Deepak Ailani, Hai Hoang Bui, Astrid van Rens, Dirk J. Lefeber, Ryan B. MacDonald, Anthony H.V. Schapira, Oliver Bandmann

The paper investigates the additive effect of genetic risk variants for Parkinson's disease and finds an unexpected rescue effect on neuronal function and survival in zebrafish with combined GCase and ASM deficiency.

bioRxiv · Jul 14, 2019 · PreprintNeuroscience