Mark Dunning

This study shows how different IDRs in CBP regulate its condensate properties, affecting gene expression and histone acetylation.

Endothelial Twist1 drives partial and advanced endothelial-to-mesenchymal transition via PELP1 and AEBP1-COL4A1 signaling, increasing collagen and ACTA2+ cells to stabilize atherosclerotic plaques in male mice and human carotid arteries.

This study identifies dysfunctional microglia in a zebrafish model of RNASET2-deficient leukoencephalopathy as a key contributor to pathological apoptosis and behavioral defects.

The paper investigates the additive effect of genetic risk variants for Parkinson's disease and finds an unexpected rescue effect on neuronal function and survival in zebrafish with combined GCase and ASM deficiency.

This study evaluates the use of Oxford Nanopore MinION long-read sequencing for detecting mtDNA deletions in mitochondrial disease diagnostics, finding it effective for large deletions but less reliable for single nucleotide variants.