Nan Li

This study shows that UPF1 deficiency in cancer cells causes replication stress but also drug resistance by reducing replication fork stalling and DNA repair pathway activation.

This study identifies SOD1 as a key factor in mitotic DNA damage response, showing it mediates mitotic delay and DNA repair, with distinct pathways for repair or progression.

The paper creates a central repository for zebrafish developmental genomics data, identifies new cis-regulatory elements, and compares regulatory elements between zebrafish and mouse.

The paper investigates the additive effect of genetic risk variants for Parkinson's disease and finds an unexpected rescue effect on neuronal function and survival in zebrafish with combined GCase and ASM deficiency.