Multi-parametric thrombus profiling microfluidics detects intensified biomechanical thrombogenesis associated with hypertension and aging
Misbahud Din, Souvik Paul, Sana Ullah, Haoyi Yang, Rong-Guang Xu, Nurul Aisha Zainal Abidin, Allan Sun, Yiyao Catherine Chen, Rui Gao, Bari Chowdhury, Fangyuan Zhou, Stephenie Rogers, Mariel Miller, Atreyee Biswas, Liang Hu, , Yunfeng Chen
This paper introduces a microfluidics-based thrombus profiling assay that detects intensified biomechanical thrombogenesis in hypertension and aging, revealing a GPIb-integrin mechanosensing axis hyperactivity mechanism.
Nature Communications · Oct 21, 2024Peer-reviewedBioengineering