Yunfeng Chen

This paper introduces a microfluidics-based thrombus profiling assay that detects intensified biomechanical thrombogenesis in hypertension and aging, revealing a GPIb-integrin mechanosensing axis hyperactivity mechanism.

This study investigates how platelet interactions with soluble and immobilized von Willebrand factor differ in their effects on adhesion, aggregation, and thrombosis, suggesting selective inhibition of aggregation as a therapeutic strategy.