Lining Arnold Ju

The paper develops a patient-specific artery-on-chip platform to study flow-dependent VWF mechanobiology and guide personalized antithrombotic therapy.

The paper uses flow molecular dynamics simulations to study how mechanical forces regulate von Willebrand factor's conformational changes through glycan-modulated autoinhibitory modules.

The paper develops a platform for automated vessel-on-chip fabrication and a generative AI model, CLoT, to predict thrombosis in patients with high accuracy.

This paper introduces a thermophoresis-based method to create stiffness gradient hydrogels and demonstrates their impact on cell morphology and migration.

The paper shows TMEM63 proteins function as mechanically activated lipid scramblases, modulated by cholesterol, contributing to membrane resilience.

This study investigates how DNA partitioning affects the phase behavior and dynamics of FUS condensates, revealing its role in modulating liquid-to-solid transitions and microstructure over time.

This paper introduces a microfluidics-based thrombus profiling assay that detects intensified biomechanical thrombogenesis in hypertension and aging, revealing a GPIb-integrin mechanosensing axis hyperactivity mechanism.