Comprehensive epigenome characterization reveals diverse transcriptional regulation across human vascular endothelial cells
Ryuichiro Nakato, Youichiro Wada, Ryo Nakaki, Genta Nagae, Yuki Katou, Shuichi Tsutsumi, Natsu Nakajima, Hiroshi Fukuhara, Atsushi Iguchi, Takahide Kohro, Yasuharu Kanki, Yutaka Saitō, Mika Kobayashi, Akashi Izumi-Taguchi, Naoki Osato, , Katsuhiko Shirahige
The paper characterizes the transcriptomic and epigenomic landscape of nine human endothelial cell types, identifying EC-specific enhancers and marker genes, and highlights the role of HOX genes in vascular development and disease.
Epigenetics & Chromatin · Dec 1, 2019Peer-reviewedGenomics