Author

Shuichi Tsutsumi

Research Center for Advanced Science and Technology, The University of Tokyo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Hiroshi KimurâiD· 2 shared Hiroyuki AburataniiD· 2 shared Ryo Nakaki· 2 shared Yasuharu KankiiD· 2 shared Youichiro WadaiD· 2 shared Akashi Izumi-Taguchi· 1 shared Akashi Taguchi· 1 shared Akihito OtsukiiD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMolecular Biology

Hiroshi KimurâORCID

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3 papers

Recent·Most cited

JG2: an updated version of the Japanese population-specific reference genome

Sirawit Sriwichaiin, Satoshi Makino, Takamitsu Funayama, Akihito Otsuki, Junko Kawashima, Yasunobu Okamura, Shu Tadaka, Fumiki Katsuoka, Kazuki Kumada, Shuichi Tsutsumi, Kengo Kinoshita, Masayuki P. Yamamoto, Gen Tamiya, Jun Takayama

This paper updates the Japanese population-specific reference genome JG1 to JG2 using Hi-C and meta-assembly methods, improving coverage and accuracy for genetic research.

Human Genome Variation · Oct 1, 2025Peer-reviewedGenomics

Coordinated demethylation of H3K9 and H3K27 is required for rapid inflammatory responses of endothelial cells

Yoshiki Higashijima, Yusuke Matsui, Teppei Shimamura, Ryo Nakaki, Nao Nagai, Shuichi Tsutsumi, Yohei Abe, Verena M. Link, Mizuko Osaka, Masayuki Yoshida, Ryo Watanabe, Toshihiro Tanaka, Akashi Taguchi, Mai Miura, Xiaoan Ruan, , Yasuharu Kanki

The paper shows that KDM7A and UTX demethylate repressive histone marks to enable NF-κB-dependent inflammatory gene activation in endothelial cells.

The EMBO Journal · Mar 3, 2020Peer-reviewedMolecular Biology

Comprehensive epigenome characterization reveals diverse transcriptional regulation across human vascular endothelial cells

Ryuichiro Nakato, Youichiro Wada, Ryo Nakaki, Genta Nagae, Yuki Katou, Shuichi Tsutsumi, Natsu Nakajima, Hiroshi Fukuhara, Atsushi Iguchi, Takahide Kohro, Yasuharu Kanki, Yutaka Saitō, Mika Kobayashi, Akashi Izumi-Taguchi, Naoki Osato, , Katsuhiko Shirahige

The paper characterizes the transcriptomic and epigenomic landscape of nine human endothelial cell types, identifying EC-specific enhancers and marker genes, and highlights the role of HOX genes in vascular development and disease.

Epigenetics & Chromatin · Dec 1, 2019Peer-reviewedGenomics