Author

Aurora Mattson-Hughes

University of Washington

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1

Frequent Co-Authors

David Joseph MarcinekiD· 2 shared Arjune DhanekulaiD· 1 shared Benjamin R. HarrisoniD· 1 shared Billiana Hwang· 1 shared Christopher R. BurkeiD· 1 shared Ethan L. OstromiD· 1 shared Gavin A. PharaohiD· 1 shared Jay D. PaliD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCell Biology

David Joseph MarcinekORCID

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2 papers

Recent·Most cited

Mitochondrial Dysfunction Drives Age-Related Degeneration of the Thoracic Aorta

Arjune Dhanekula, Benjamin R. Harrison, Gavin A. Pharaoh, Aurora Mattson-Hughes, Stefano Tarantini, Rudolph S. Stuppard, Scott C. DeRoo, Christopher R. Burke, Billiana Hwang, Jay D. Pal, Michael S. Mulligan, David Joseph Marcinek

This study shows that mitochondrial dysfunction contributes to aortic aging and that treatment with elamipretide improves mitochondrial function and reduces inflammation in aged mice.

GeroScience · Nov 13, 2025Peer-reviewedCell Biology

Inducible and reversible SOD2 knockdown in mouse skeletal muscle drives impaired pyruvate oxidation and reduced metabolic flexibility

Ethan L. Ostrom, Rudy Stuppard, Aurora Mattson-Hughes, David Joseph Marcinek

This study shows that inducible SOD2 knockdown in mouse skeletal muscle reduces metabolic flexibility by impairing pyruvate oxidation, with reversible effects upon recovery.

Free Radical Biology and Medicine · Nov 15, 2024Peer-reviewedPhysiology