Author

Ethan L. Ostrom

Northern Arizona UniversityORCID 0000-0002-7400-2821Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

David Joseph MarcinekiD· 2 shared Ana P. ValenciaiD· 1 shared Aurora Mattson-Hughes· 1 shared Rudy Stuppard· 1 shared Tinna TraustadóttiriD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

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5 top collaborators · 6 mutual co-author links

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2 shared papersPhysiology

David Joseph MarcinekORCID

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2 papers

Recent·Most cited

PhysiologyFree Radical Biology and MedicinePeer-reviewedNov 15, 2024

Inducible and reversible SOD2 knockdown in mouse skeletal muscle drives impaired pyruvate oxidation and reduced metabolic flexibility

Ethan L. Ostrom, Rudy Stuppard, Aurora Mattson-Hughes, David Joseph Marcinek

This study shows that inducible SOD2 knockdown in mouse skeletal muscle reduces metabolic flexibility by impairing pyruvate oxidation, with reversible effects upon recovery.

7 citations

mouseproteomics

𝕏 PostBluesky

Molecular BiologyFree Radical Biology and MedicinePeer-reviewedAug 1, 2021

High intensity muscle stimulation activates a systemic Nrf2-mediated redox stress response

Ethan L. Ostrom, Ana P. Valencia, David Joseph Marcinek, Tinna Traustadóttir

This study compares high and low intensity muscle stimulation on Nrf2-mediated redox stress responses in mouse skeletal muscle, finding intensity-dependent activation of Nrf2-ARE binding and downregulation of Keap1.

31 citations

mousestatistical model

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