Author

Austin Cozzone

Children's Hospital of Philadelphia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Alexandra NeeseriD· 2 shared Leyuan MaiD· 2 shared Ryan TanniriD· 2 shared Tomasz M. GrzywaiD· 2 shared Anna Romanov· 1 shared Arjun Ramamurthi· 1 shared Beatriz Goncalves· 1 shared Benjamin Cossette· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersBioengineering

Alexandra NeeserORCID

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2 papers

Recent·Most cited

Enhanced lentiviral gene delivery to mammalian cells via paired cell surface and viral envelope engineering

Ryan Tannir, Letitia Chan, Tomasz M. Grzywa, Orlando D. Arevalo, Alexandra Neeser, Sara Kahn, Austin Cozzone, Arjun Ramamurthi, Lauren K. Olenick, Nicola J. Mason, Xue‐Yuan Liu, Leyuan Ma

This paper improves lentiviral gene delivery to mammalian cells by engineering virus-envelope and cell-surface interactions using FITC labeling and chimeric envelopes.

Molecular Therapy Advances · Jan 3, 2026Peer-reviewedBioengineering

Directed evolution-based discovery of ligands for in vivo restimulation of CAR-T cells

Tomasz M. Grzywa, Alexandra Neeser, Ranjani Ramasubramanian, Anna Romanov, Ryan Tannir, Naveen K. Mehta, Benjamin Cossette, Duncan M. Morgan, Beatriz Goncalves, Ina Sukaj, Elisa Bergaggio, Stephan Kadauke, Regina M. Myers, Luca Paruzzo, Guido Ghilardi, , Darrell J. Irvine

This study develops a method to generate optimized peptide ligands for CAR-T cell restimulation, demonstrating enhanced expansion and memory development in preclinical models.

bioRxiv · Apr 16, 2024 · PreprintBioengineering