Author

Austin R. Harrington

University of California San Diego

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2

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Approach:experimental assay· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Chun ZengiD· 2 shared Fenfen Liu· 2 shared Han ZhuiD· 2 shared Maike SanderiD· 2 shared Matthew WorthamiD· 2 shared Somesh SaiiD· 2 shared Bastian RammsiD· 1 shared Bradley Liu· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersPhysiology

Chun ZengORCID

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2 papers

Recent·Most cited

PhysiologybioRxivPreprintMay 18, 2026

Workload-induced changes to cell state contribute to β-cell failure in diabetes

Somesh Sai, Fenfen Liu, Austin R. Harrington…·Matthew Wortham

This study shows workload-induced β-cell overstimulation leads to failure in T2D, identifying a compensating transcriptional state and the role of Lsd1 in restraining state transitions.

DOI 10.64898/2026.05.13.725004

mousescRNA-seq

𝕏 PostBluesky

PhysiologyJournal of Clinical InvestigationPeer-reviewedJul 31, 2025

Metabolic control of adaptive β-cell proliferation by the protein deacetylase SIRT2

Matthew Wortham, Bastian Ramms, Chun Zeng…·Maike Sander

This study identifies SIRT2 as a regulator of β-cell proliferation, showing its role in controlling β-cell expansion during hyperglycemia while preserving feedback mechanisms.

9 citationstop 5%

mousehuman

𝕏 PostBluesky